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pCR1000DQB1*0607

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編號:B242623

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產品名稱	pCR1000DQB1*0607
商品貨號	B242623
Designations	pCR1000DQB1*0607
GenBank Number	M87041
Species	Homo sapiens, human
Depositors	L Baxter-Lowe
Vector	Construct size (kb): 3.269999980926514 DESCRIPTION OF VECTOR COMPONENT: Name of vector: pCR1000 Intact vector size: 3.000 Type of vector: plasmid Vector end: T overhangs Vector end: T overhangs Cloning sites: Polylinker sites: ApaI KpnI SacI SpeI PacI HindIII XmaI ins site NotI EcoRI Host range: Escherichia coli Features (with orientation and position when available): insert detection: lacZ' marker(s): kanR promoter: lac, T7 replicon: colE1 Cross references:
Insert	DNA: genomic DESCRIPTION OF INSERT COMPONENT: Genome: Homo sapiens Gene symbol: HLA-DQB1 Other gene symbols: HLA-DQB Genomic copy number: unique Gene name: major histocompatibility complex, class II, DQ beta 1 Contains complete coding sequence?: U Chromosome: 6; Localization: 6 p21.3 Tissue: peripheral blood leukocytes Type of DNA: genomic Insert end: Modification: A overhangs Insert end: Modification: A overhangs Insert size (kb): 0.27 Cross references: DNA Seq. Acc.: M87041 Insert lengths(kb): 0.2700000107288361 Tissue: peripheral blood leukocytes Gene product: major histocompatibility complex, class II, DQ beta 1(major histocompatibility complex, class II, lymphocyte antigen DQB) [HLA-DQB]
Insert Size (kb)	0.270
Media	ATCC^® Medium 1236: LB Medium (ATCC medium 1065) with 25 mcg/ml kanamycin
Biosafety Level	1 Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Shipping Information	Distributed: freeze-dried
Comments	Restriction digests of the clone give the following sizes (kb): BglI--2.9, 0.38; SmaI--2.8, 0.4, 0.2; BamHI--uncut; EcoRI/HindIII--3.0, 0.32; HindIII--3.3. The insert contains the following restriction sites (bp from the 5' end): BglI--129; SmaI--188. Encodes the 0607 or the 06BRI1 allele, which differs from DQB1*0603 by a substitution at codon 57 [GTT (valine) replacing GAT (aspartic acid)].
References	Fenske TS, Baxter-Lowe LA. Two novel HLA-DQB1*06 alleles reveal additional heterogeneity of HLA-DQw1. Tissue Antigens 40: 49-52, 1992. PubMed: 1440562

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