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LRP06

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編號(hào):B215179

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產(chǎn)品名稱	LRP06
商品貨號(hào)	B215179
Designations	LRP06
GenBank Number	X13916
Species	Homo sapiens, human
Vector	Construct size (kb): 8.859999656677246
Insert	DNA: cDNA Insert lengths(kb): 5.991000175476074 Tissue: liver Gene product: low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)(apoE receptor, apolipoprotein receptor, low density lipoprotein receptor-related (LDL-receptor related), lrp) [APR]
Insert Size (kb)	5.991
Biosafety Level	1 Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Shipping Information	Distributed: DNA (dried). Rehydrate with TE. (amount: 200 ng)
Comments	Restriction digests of the clone give the following sizes (kb): XhoI/EcoRI--6.0, 2.9; EcoRI--8.9; HindIII--uncut; BamHI--6.8, 2.2; PvuII--5.8, 3.0. The insert contains the following restriction sites, in approximate kb from the 5' end: SalI--1.35; BamHI--2.24, 4.46, 4.47; PvuII--5.63, 5.80; EcoRI--5.986. Extends from nt 188 to nt 6179 of the submitted sequence, containing part of the coding sequences which extend from nt 467 to nt 14104 of the 14.896 kb cDNA.
References	Herz J, et al. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J. 7: 4119-4127, 1988. PubMed: 3266596 Myklebost O, et al. The gene for the putative apoE receptor is on chromosome 12 in the segment q13-q14. Genomics 5: 65-69, 1989. PubMed: 2548950 Strickland DK, et al. Sequence identity bwteen the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor. J. Biol. Chem. 265: 17401-17404, 1990. PubMed: 1698775 Kristensen T, et al. Evidence that the newly cloned low-density-lipoprotein receptor-related protein (LRP) is the alpha-2-macroglobulin receptor. FEBS Lett. 276: 151-155, 1990. PubMed: 1702392 Joachim Herz, personal communication

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