Leptodontidium elatius (Mangenot) de Hoog var. elatius, anamorph
商品貨號
B195647
Strain Designations
MF5465 [CIBE 8943-106F, Mycosearch 3137]
Application
produces squalene synthetase inhibitor
produces zaragozic acid C
produces zaragozic acid E
produces zaragozic acid F
produces zaragozic acid C, a squalene synthetase inhibitor
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
freeze-dried
Type Strain
no
Disclosure
This material is cited in a US or other Patent and may not be used to
infringe the claims. Depending on the wishes of the Depositor, ATCC may be
required to inform the Patent Depositor of the party to which the material was
furnished. This material may not have been produced or characterized by ATCC.
dead wood, Joyce Kilmer Memorial Forest, Graham Co., NC
References
Bartizal KF, Onishi JC. Method of inhibiting fungal growth using squalene synthetase inhibitors. US Patent 5,026,554 dated Jun 25 1991
Bergstrom JD, et al. Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase. Proc. Natl. Acad. Sci. USA 90: 80-84, 1993. PubMed: 8419946
Bills GF, et al. Distribution of zaragozic acids (squalestins) among filamentous ascomycetes. Mycol. Res. 98: 733-739, 1994.
