| Comments |
Restriction digests of the clone give the following sizes (kb): EcoRI--19.8, 10.9, 7.8, 5.2, 1.9. This insert extends from 7 kb upstream to 5 kb downstream of the 2 kb EcoRI fragment containing sequences homologous to the pE-301 cDNA clone (ATCC 57020, 57021). Contains the complete gene with 3 intervening sequences, the cap site, a polyadenylation signal, and Alu sequences in both the 5' and 3' flanking region. Exon 4 contains 66 bp tandem repeats. |
| References |
Das HK, et al. Isolation, characterization, and mapping to chromosomse 19 of the human apolipoprotein E gene. J. Biol. Chem. 260: 6240-6247, 1985. PubMed: 3922972
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