Monoclonal Anti-Dengue virus type 4 envelope protein, Clone E40 (produced in vitro)
商品貨號
B163238
Classification
Flaviviridae, Flavivrus
Agent
Monoclonal Anti-Dengue virus type 4 envelope protein, Clone E40 (produced in vitro)
Biosafety Level
1
Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format
frozen
Storage Conditions
-20°C or colder. Repeated freeze-thaw cycles should be avoided.
Comments
Antibody Class: IgG2aκ
The B cell hybridoma was generated by the fusion of P3X63.Ag.8.6.5.3 BALB/c mouse myeloma cells with immunized mouse splenocytes.
Name of Depositor
MS Diamond, Washington University in St. Louis, School of Medicine
Source
Mouse monoclonal antibody prepared against the envelope glycoprotein of Dengue virus type 4 (DEN-4) was purified from clone E40 hybridoma supernatant by protein G affinity chromatography.
References
Balsitis SJ, et al. Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification. PLoS Pathog. 6: e1000790, 2012. PubMed: 20168989
Rajamanonmari R, et al. On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes. J. Gen. Virol. 90: 799-809, 2009. PubMed: 19264660
